6 Ways to Reduce Prescription Benefit Costs, Keep Access
- Christopher Johnson
- 1 day ago
- 5 min read

Introduction If you’re looking to reduce prescription benefit costs without blocking access to essential medications, the playbook blends prevention, smarter contracts, and clinical discipline. Below is a quick summary of what follows:
Pair evidence-based prescribing with targeted nutrition to avoid unnecessary drugs
Use value-based contracts so payment tracks real-world outcomes
Fund prevention and manage formularies to favor effective, affordable options
Align copays with clinical value using value-based insurance design
Audit formularies and partner with pharmacists to curb low‑value spending
Prioritize essential and preventive drugs, and demand pricing transparency
In the sections below, you’ll find expert quotes and context that show how to reduce prescription benefit costs while protecting access to the medications that matter most.

Integrate Nutrition with Pharmaceuticals to Reduce Prescription Benefit Costs
Thoughtful benefit design starts upstream. When patients receive precision nutrition alongside appropriate prescribing, total drug load can fall and adherence often improves. In practice, that means building protocols that let clinicians use clinical‑grade supplements where evidence supports them, while still centering safe, guideline‑based care. Employers can reinforce the approach with wellness incentives that reduce avoidable utilization and keep people engaged in preventive care. Health analytics help here too. Stratify risk, flag rising‑risk members, and intervene early to avoid complications that trigger high‑cost prescriptions later. Formulary negotiations should be tied to effectiveness standards, not brand familiarity. That pushes spend toward drugs with proven benefit and away from marginal options. The throughline is simple: combine transparency, prevention, and evidence so fewer people need multiple medications in the first place, and those who do get the right ones at sustainable prices.
Quote (kept verbatim):
“Prescription benefit programs can be optimized by combining traditional pharmaceutical management with integrative health practices… Ultimately, an overall strategy integrating cutting‑edge nutrition, transparency, and evidence‑based initiatives allows providers and employers alike to simultaneously keep costs contained and provide patient access to required medications.”

Dr. Richard Drucker, Board Certified Founder & CEO, Drucker Labs
Value‑Based Contracts Drive Better Prescription Benefit Results
Tying payment to outcomes realigns everyone’s incentives. With value‑based contracts, a therapy that underperforms financially underperforms for the manufacturer too. That pushes price toward demonstrated effectiveness and reduces waste from drugs that don’t deliver for specific populations. For employers, these contracts can be layered onto PBM relationships and focused on high‑impact categories like cardiometabolic disease, inflammatory conditions, oncology support meds, and specialty generics where competition is emerging. Success requires real‑world evidence, clear definitions of “success,” and data‑sharing across stakeholders. Done well, you reduce prescription benefit costs while maintaining access to essential medications for the patients who benefit most.
Quote (kept verbatim):
“Through negotiated outcome‑based pricing, payment is decided through the drug’s effectiveness… employers are effectively reducing costs while keeping access to essential medications.”

Robert Applebaum, CEO & Plastic Surgeon, Beverly Hills Breast Reduction Center
Prevention and Formulary Management Cut Prescription Costs
The cheapest prescription is the one you never need. Fund prevention fully, including dental, because oral health issues can drive systemic disease and downstream drug spend. Make routine visits zero‑cost to members, communicate why early care reduces long‑term medication reliance, and measure engagement as a core KPI. On the formulary side, schedule regular reviews to elevate generics and therapeutically equivalent options. Educate prescribers on preferred alternatives and make switches easy at the point of care. When prevention and formulary hygiene move together, spend trends flatten without harming outcomes.
Quote (kept verbatim):
“Prevention is key to managing prescription benefit costs… Periodic evaluation of lists of drugs to rank generics and affordable therapies keeps the costs in check without compromising on quality.”

Dr Stacey Laskis, Dentist, Parkview Dentistry

Value‑Based Insurance Design Aligns Medication Costs with Benefits
Value‑based insurance design (VBID) brings member cost‑sharing in line with clinical value. Lower or eliminate copays for high‑value medications with strong evidence. Maintain higher cost‑sharing for low‑value options to nudge choices without cutting access. Pair VBID with prescriber education, extended fills for stable regimens, and proactive patient communication so people understand their lower out‑of‑pocket costs on the most effective therapies. The result is better adherence where the evidence is strongest and fewer dollars wasted on low‑impact drugs.
Quote (kept verbatim):
“I think that healthcare professionals and employers must implement value‑based insurance design that aligns the patient’s out‑of‑pocket expenses with the real clinical value of medication… design benefit programs that are innovative, efficient, and most importantly, patient‑centered.”

Dr. Avi Israeli, Co‑Founder and Dental Implantologist, Sage Dental NJ
Formulary Audits Yield Savings Without Compromising Care
Routine audits catch legacy prescribing and low‑value drugs that linger due to habit. Start by ranking categories with the biggest spend and variance. Identify therapeutically equivalent, lower‑cost options and refresh order sets, EMR defaults, and pharmacist protocols to support substitution. Collaboration with pharmacists is pivotal. They spot adherence issues, recommend alternatives with better refill rates, and help shape education that sticks. Treat this as a clinical quality initiative, not only a cost exercise, and you’ll see savings plus better patient experience.
Quote (kept verbatim):
“Regular formulary audit… With only minor revisions to our internal processes and staff retraining, we achieved significant cost savings without compromising care… The other significant step was the increased collaboration with pharmacists… What makes cost‑cutting become actual care improvement is close collaboration between clinical and administrative teams.”

Ben Waismann, CEO, ANR Clinic

Prioritize Essential and Preventive Drugs in Benefits
Anchor your benefit around an essential medicines list that reflects population needs, then verify that access is real at the point of care. Budget explicitly for preventive drugs that avert costly downstream treatment. Align coverage criteria with local epidemiology, update at least annually, and publish transparent pricing so members know what to expect. These moves protect access to essential medications while bending the trend on total pharmacy spend.
Quote (kept verbatim):
“Essential drugs should follow their principle of satisfying the health needs of the population… Preventive care drugs should get priority… Transparency in drug pricing is another important thing with the prescription benefits, and these drugs should always be available at very minimal cost.”

Austin Anadu, Medical Doctor, AlynMD
Final Takeaway
Across these six plays, the pattern is clear. Use prevention and formularies to cut waste early. Pay for outcomes with value‑based contracts. Align out‑of‑pocket costs with clinical value through VBID. Audit relentlessly, and let pharmacists co‑lead the work. Prioritize essential and preventive drugs, and publish prices. Do these things together and you’ll reduce prescription benefit costs while maintaining access to essential medications for the people who need them most.